Gastroesophageal physiology after stapled gastroesophagostomy in dogs.

Autor: Edwards M; Department of Surgery, Southern Illinois University School of Medicine, Springfield 62794-9230., Mortenson D, Vasudeva R, Holt S, Folse JR
Jazyk: angličtina
Zdroj: American journal of surgery [Am J Surg] 1992 Jun; Vol. 163 (6), pp. 581-4.
DOI: 10.1016/0002-9610(92)90561-5
Abstrakt: A stapled vertical gastroesophagostomy (VGE) has been proposed for benign esophageal stricture. The VGE involves performing an anastomosis using a linear cutting stapler inserted via a gastrotomy (one limb in the esophagus, the other in the proximal fundus). In phase I of the study, a 50-mm VGE was performed in 13 dogs; 7 received an additional fundoplication. Endoscopy with pinch biopsies, esophageal manometry, and 4-hour ambulatory pH recordings were performed in each dog prior to and 1 month after VGE. The only difference between groups postoperatively was a higher lower esophageal sphincter pressure in the group with the added fundoplication. The incidence of histologic esophagitis was low in both groups. In phase II of the study, a VGE was performed in six dogs using a 75-mm linear cutting stapler, accompanied by fundoplication in each dog. These dogs were then followed for 6 months to more completely assess the long-term risk of developing reflux esophagitis. At necropsy, no gross or histologic evidence of esophagitis was found. The performance of a VGE through the lower esophageal sphincter in normal dogs does not result in significant reflux esophagitis. VGE may be an alternative to resection for esophageal stricture.
Databáze: MEDLINE