Biochemical perspectives on paralysis and other forms of toxicoses caused by ticks.

Autor: Mans BJ; Department of Biochemistry, University of Pretoria, Pretoria, 0002, South Africa., Gothe R, Neitz AW
Jazyk: angličtina
Zdroj: Parasitology [Parasitology] 2004; Vol. 129 Suppl, pp. S95-111.
DOI: 10.1017/s0031182003004670
Abstrakt: Tick toxicoses, of which paralysis is the most widespread and dominant form, are important elements of pathogenesis induced by ticks. Tick paralysis is the most widespread and dominant form of tick toxicoses. Non-paralytic forms of tick toxicoses do occur and evidence suggests that these forms of toxicoses are not evolutionary related. While functional significance has been suggested for tick toxins, the advantages for tick survival in general are not clear. This review considers the molecular nature of tick toxins, the possibility that tick toxins have originated more than once independently and whether these toxins could have unrecognized benign functions.
Databáze: MEDLINE