| Autor: |
Sevan'kaev AV, Shkavrova TG, Potetnia OI, Mikhaĭlova GF, Tsepenko VV, Golub EV, Khvostunov IK, Saenko AS, Gasteva GN, Nugis VIu, Molokanov AA |
| Jazyk: |
ruština |
| Zdroj: |
Radiatsionnaia biologiia, radioecologiia [Radiats Biol Radioecol] 2005 Mar-Apr; Vol. 45 (2), pp. 149-61. |
| Abstrakt: |
A study of frequency of unstable chromosome aberrations in 50 workers of nuclear chemical plants in remote period after beginning or finishing professional contact with ionizing radiation was carried out. 14 persons from this cohort were mainly whole-body exposed to external gamma-rays and 36 were exposed to combined external and internal radiation from incorporated Pu nuclides. In results of this irradiating practically every subject had a chronical radiation sickness. In the 1-st group the frequency of unstable aberrations varied from 0.2 to 3.6 per 100 cells and exceeded reliably control level in 5 persons. In the 2-nd group the frequency of unstable aberrations varied from 0 to 11.6 per 100 cells and exceeded reliably control level in 20 examined workers. The FISH study of frequency of stable aberrations was performed in 13 subjects who were exposed to combined external and internal radiation. Total frequency of complete and incomplete translocations varied from 0.6 to 18.5 aberrations per genome per 100 cells and reliable exceeded control level in 9 subjects. Non-random participation in exchange rearrangements (translocations) was revealed for used set of chromosomes (2, 3 and 8). |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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