| Autor: |
Khan S; Rothamsted Research, Harpenden, Hertfordshire AL5 2LQ, United Kingdom., Reynolds AM, Morrison IE, Cherry RJ |
| Jazyk: |
angličtina |
| Zdroj: |
Physical review. E, Statistical, nonlinear, and soft matter physics [Phys Rev E Stat Nonlin Soft Matter Phys] 2005 Apr; Vol. 71 (4 Pt 1), pp. 041915. Date of Electronic Publication: 2005 Apr 29. |
| DOI: |
10.1103/PhysRevE.71.041915 |
| Abstrakt: |
A simple model in which immobilizing events are imposed onto otherwise free Brownian diffusion [R. Metzler and J. Klafter, Phys. Rep. 339, 1 (2000) and a recent adaptation due to S. Khan and A. M. Reynolds, Physica A 350, 183 (2005)] is shown to encapsulate the peculiar transport characteristics of individual cell receptors within plasma membranes observed in single-particle tracking (SPT) experiments. These characteristics include the occurrence of normal diffusion; non-Gaussian subdiffusion; confined diffusion; a superdiffusive mode of transport that is not due to flow of the membrane or molecular motor attachment; and the occurrence of transitions between these transport modes. Model predictions are shown to be in close agreement with a reanalysis of existing SPT data. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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