| Autor: |
Gunn D; Bayer Research Center, Bayer HealthCare Pharmaceuticals, 400 Morgan Lane, West Haven, CT 06516, USA. david.gunn.b@bayer.com, Akuche C, Baryza J, Blue ML, Brennan C, Campbell AM, Choi S, Cook J, Conrad P, Dixon B, Dumas J, Ehrlich P, Gane T, Joe T, Johnson J, Jordan J, Kramss R, Liu P, Levy J, Lowe D, McAlexander I, Natero R, Redman AM, Scott W, Seng T, Sibley R, Wang M, Wang Y, Wood J, Zhang Z |
| Jazyk: |
angličtina |
| Zdroj: |
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2005 Jun 15; Vol. 15 (12), pp. 3053-7. |
| DOI: |
10.1016/j.bmcl.2005.04.025 |
| Abstrakt: |
4,5-Disubstituted cis-pyrrolidinones were investigated as inhibitors of type II 17beta-hydroxysteroid dehydrogenase (17beta-HSD). Early structure-activity relationship patterns for this class of compounds are discussed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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