Distribution of CCR5-delta32, CCR2-64I, and SDF1-3'A mutations in populations from the Brazilian Amazon region.

Autor: De Pinho Lott Carvalhaes FA; Laboratory of Human and Medical Genetics, Department of Pathology, Center for Biological Sciences, Federal University of Pará, 66075-900 Belém, Para, Brazil., Cardoso GL, Hamoy IG, Liu YT, Guerreiro JF
Jazyk: angličtina
Zdroj: Human biology [Hum Biol] 2004 Aug; Vol. 76 (4), pp. 643-6.
DOI: 10.1353/hub.2004.0052
Abstrakt: The frequency distribution of the CCR5-delta32, CCR2-64I, and SDF1-3'A alleles was studied in the urban population of Belém and in Afro-Brazilians, Amerindians, and Japanese immigrants in the state of Pará, Brazil. The results suggest that Amerindians may be genetically more susceptible to HIV-1 infection and disease progression than the other human groups studied.
Databáze: MEDLINE