| Autor: |
Bekhit AA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Alexandria, Egypt., El-Sayed OA, Aboul-Enein HY, Siddiqui YM, Al-Ahdal MN |
| Jazyk: |
angličtina |
| Zdroj: |
Archiv der Pharmazie [Arch Pharm (Weinheim)] 2005 Mar; Vol. 338 (2-3), pp. 74-7. |
| DOI: |
10.1002/ardp.200400930 |
| Abstrakt: |
Three structurally related aminopyrazoloquinoline derivatives were evaluated for their antiviral activity against Herpes Simplex virus type 1. These compounds were examined for their in vitro antiviral activity by two different bioassays, namely; crystal violet staining and tetrazolium dye (MTS) measurement. The antiviral role of these compounds was confirmed by enumerating the infectious particles with plaque assay. The acute toxicity values of the biologically active compounds were determined prior to their screening as antiviral agents. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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