Experimental bacteriophage protection against Staphylococcus aureus abscesses in a rabbit model.

Autor: Wills QF; Infectious Diseases and Microbiology Unit, Institute of Child Health, University College London, UK., Kerrigan C, Soothill JS
Jazyk: angličtina
Zdroj: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2005 Mar; Vol. 49 (3), pp. 1220-1.
DOI: 10.1128/AAC.49.3.1220-1221.2005
Abstrakt: In a rabbit model of wound infection caused by Staphylococcus aureus, 2 x 10(9) PFU of staphylococcal phage prevented abscess formation in rabbits when it was injected simultaneously with S. aureus (8 x 10(7) CFU) into the same subcutaneous site. Phage multiplied in the tissues. Phages might be a valuable prophylaxis against staphylococcal infection.
Databáze: MEDLINE