| Autor: |
Mahmoudian T; Department of Child Neurology, Medical University of Isfahan, Isfahan, Iran. t_mahmoudian@med.mui.ac.ir, Iranpour R, Messri N |
| Jazyk: |
angličtina |
| Zdroj: |
Epilepsy & behavior : E&B [Epilepsy Behav] 2005 Mar; Vol. 6 (2), pp. 257-9. |
| DOI: |
10.1016/j.yebeh.2004.11.013 |
| Abstrakt: |
The aim of the study was to evaluate serum lipid levels during carbamazepine therapy in epileptic children. Thirty epileptic children (18 male, 12 female; age range, 30 months to 14 years) with idiopathic or cryptogenic partial or generalized tonic-clonic seizures (13 CPS, 17 GTC) were evaluated for serum lipids at the onset and the third month of carbamazepine therapy. Carbamazepine was started at 10 mg/kg/day. Mean total cholesterol, low-density lipoprotein, very low density lipoprotein, and triglyceride levels significantly increased during treatment (P < 0.05), but mean high-density lipoprotein levels were not statistically significant throughout the study. Carbamazepine treatment alters the serum lipid profile of children in such a way that it could potentially facilitate the development of atherosclerosis. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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