Skin model surface temperatures during single and multiple cryogen spurts used in laser dermatologic surgery.

Autor: Ramirez-San-Juan JC; Beckman Laser Institute and Medical Clinic, University of California, Irvine, California 92612, USA., Aguilar G, Tuqan AT, Kelly KM, Nelson JS
Jazyk: angličtina
Zdroj: Lasers in surgery and medicine [Lasers Surg Med] 2005 Feb; Vol. 36 (2), pp. 141-6.
DOI: 10.1002/lsm.20124
Abstrakt: Background: Although cryogen spray cooling (CSC) is used to minimize the risk of epidermal damage during laser dermatologic surgery, concern has been expressed that CSC may induce cryo-injury. In order to address this concern, it is necessary to evaluate the effects of prolonged exposure of human skin phantoms (HSP) to CSC.
Objective: To measure the minimum surface temperature (T(min)) and the time at which it occurs (t(Tmin)) as well as determine the time the sprayed HSP surface remains below 0 degrees C (sub-zero time, Deltat(s)) and -26 degrees C (residence time, Deltat(r)) during the application of single (SCS) and multiple (MCS) cryogen spurts. Two initial HSP substrate temperatures were studied, T(i): 23 and 70 degrees C.
Study Design/materials and Methods: An epoxy-based HSP was constructed to measure T(min), t(Tmin), Deltat(s), and Deltat(r), for 17 spray patterns: 1 SCS with a total cryo-delivery time (Deltat(c)) of 40 milliseconds; 8 MCS patterns with identical Deltat(c), but with a total cooling time (Deltat(total)) varying from 50 to 280 milliseconds; and 8 SCS patterns that matched the Deltat(total) of the MCS patterns.
Results: For both T(i), our results show that it is possible to distinguish between two different cooling regimes. For Deltat(total) Conclusions: These results suggest that: (1) similar epidermal protection may be attained with SCS and MCS for Deltat(total) ((c) 2005 Wiley-Liss, Inc.)
Databáze: MEDLINE
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