| Autor: |
King MD; Department of Biophysics, Hunterian Institute, Royal College of Surgeons of England, London, United Kingdom., van Bruggen N, Busza AL, Houseman J, Williams SR, Gadian DG |
| Jazyk: |
angličtina |
| Zdroj: |
Magnetic resonance in medicine [Magn Reson Med] 1992 Apr; Vol. 24 (2), pp. 288-301. |
| DOI: |
10.1002/mrm.1910240210 |
| Abstrakt: |
Diffusion-weighted images of the rat brain were obtained using the pulsed-gradient spin-echo method. An attempt was made to extract perfusion-related parameters from signal intensity data taken from the caudate-putamen region of the images, by using a nonlinear least-squares calculation to fit the Le Bihan biexponential expression (Le Bihan et al., Radiology, 168, 497 (1988)) to the data. The perfusion-related parameters could not be obtained with sufficient accuracy to be useful, although the perfusion-weighted images appear to contain meaningful qualitative information. An analysis of the perfusion model is presented and shows why the Le Bihan pseudo-diffusion coefficient is particularly difficult to measure with reasonable accuracy. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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