Immunosuppressive regimens in lung transplant recipients.

Autor: Bhorade SM; Division of Pulmonary/Critical Care Medicine, Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA. sbhorad@lumc.edu, Villanueva J, Jordan A, Garrity ER
Jazyk: angličtina
Zdroj: Drugs of today (Barcelona, Spain : 1998) [Drugs Today (Barc)] 2004 Dec; Vol. 40 (12), pp. 1003-12.
DOI: 10.1358/dot.2004.40.12.872575
Abstrakt: A lung transplant is usually the last resort treatment for lung failure. Since the introduction of cyclosporine A, success rates after solid organ transplantation began to rise, following an incremental curve over the last decade, in which further development of biological agents and newer immunosuppressive agents has continued to improve outcomes after transplantation. Pharmacokinetic and pharmacodynamic properties, as well as efficacy and safety data from clinical trials with immunosuppressive agents and biological agents currently available, are reviewed here.
((c) 2004 Prous Science. All rights reserved)
Databáze: MEDLINE