Autor: |
Totti MA; Department of Oral Pathology, School of Dentistry of Piracicaba, State University of Campinas., dos Santos EB, de Almeida OP, Koga-Ito CY, Jorge AO |
Jazyk: |
angličtina |
Zdroj: |
Brazilian oral research [Braz Oral Res] 2004 Jul-Sep; Vol. 18 (3), pp. 202-7. |
DOI: |
10.1590/s1806-83242004000300005 |
Abstrakt: |
The aim of this study was to analyze the effect of sialoadenectomy on the development of oral candidosis after one or four inoculations of Candida albicans. Initially, a suspension containing 10(8) cells/ml of C. albicans ATCC 36801 was prepared. Seventy-eight sialoadenectomized mice and a similar amount of mice with normal salivary flow received a single inoculation of C. albicans suspension. Another group with a similar number of mice received 4 inoculations. The control group consisted of 6 sialoadenectomized mice and 6 mice with normal salivary flow that were not inoculated with C. albicans. Candidosis development was studied histologically in the tongue of the animals 1, 2, 3, 5, and 8 days after inoculation and at 15-day intervals up to 165 days. According to the results obtained, it could be concluded that sialoadenectomy and a higher frequency of yeast inoculation influenced the presence and extension of candidosis lesions. |
Databáze: |
MEDLINE |
Externí odkaz: |
|