[Effects of myostatin and other growth factors on cultured human cells].

Autor: Shishkin SS, Krokhina TB, Akhunov VS, Makarov AA, Popov VO
Jazyk: ruština
Zdroj: Prikladnaia biokhimiia i mikrobiologiia [Prikl Biokhim Mikrobiol] 2004 Nov-Dec; Vol. 40 (6), pp. 630-3.
Abstrakt: A dedicated cell-based biological test system was used for studying specific effects of myostatin and other human growth factors on the proliferation of cultured myoblasts and fibroblasts. Myostatin inhibited myoblast growth without affecting human fibroblasts. In this test system, human growth hormone and insulin-like growth factor I acted as antagonists of myostatin, which indicates that these agents have a potential for blocking its effects in vivo.
Databáze: MEDLINE