Effects of hormone replacement therapy or raloxifene on ambulatory blood pressure and arterial stiffness in treated hypertensive postmenopausal women.

Autor: da Costa LS; General Hospital, Santa Casa Misericórdia of Rio de Janeiro, Rio de Janeiro, Brazil., de Oliveira MA, Rubim VS, Wajngarten M, Aldrighi JM, Rosano GM, Neto CD, Gebara OC
Jazyk: angličtina
Zdroj: The American journal of cardiology [Am J Cardiol] 2004 Dec 01; Vol. 94 (11), pp. 1453-6.
DOI: 10.1016/j.amjcard.2004.07.153
Abstrakt: The administration of oral raloxifene in 30 postmenopausal hypertensive women was evaluated to demonstrate its effect on arterial stiffness. Casual and ambulatory blood pressure (BP) and pulse-wave velocity (PWV) data were obtained before and after patients received raloxifene, estrogen-progestin replacement therapy, or placebo in a randomized crossover study. It was shown that the 2 therapies decreased BP and carotid-femoral PWV, and the effect of raloxifene on vascular compliance was independent of the effects on BP.
Databáze: MEDLINE