Autor: |
Shcherbata GR, Matiĭtsiv NP, Chernik IaI, Maksimiv DV |
Jazyk: |
ruština |
Zdroj: |
Genetika [Genetika] 2004 Sep; Vol. 40 (9), pp. 1280-5. |
Abstrakt: |
Neurodegenerative human diseases are caused by nerve cell death and anatomical changes in some brain regions. Molecular genetic studies of Drosophila showed that this organism can serve as a valuable test-system for conserved mechanisms underlying human nervous system disorders. Analysis of brain functions is possible when the mutants with disturbed functions are available. In this study, we have developed a unique collection of Drosophila melanogaster mutants with morphological and neurodegenerative changes in brain structure, which were induced by chemical mutagens. |
Databáze: |
MEDLINE |
Externí odkaz: |
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