Influence of deproteinized hemodialysate on rest pain and walking distance in the presence of peripheral chronic arterial occlusive disease.

Autor: Angelkort B; Department of Central Medicine, Municipal Hospital, Dortmund, Germany., Rühlmann KU, de la Haye R, Kuntz G
Jazyk: angličtina
Zdroj: Angiology [Angiology] 1992 Jan; Vol. 43 (1), pp. 47-58.
DOI: 10.1177/000331979204300106
Abstrakt: In a controlled and randomized single-blind study (blind observer) the clinical efficacy of intra-arterial therapy with a metabolically active deproteinized dialysate from calf blood has been tested against a vasodilating and hemorheologically active reference substance (bencyclan). Over a period of four weeks 28 patients each received 20 intra-arterial infusions of the deproteinized hemodialysate 20% for infusion. The reference group with 30 patients was treated with 250 mg bencyclan in 250 mL saline 0.9%. As for the target criteria, rest pain and consumption of analgesics, the hemodialysate treatment proved superior to the therapy with the reference substance. Both preparations induced to a small extent pain-free walking distances: hemodialysate group, 29.2 +/- 14.6 m; reference group, 25.8 +/- 18.7 m (group difference not significant).
Databáze: MEDLINE