[A virological description of serous meningitis in children immunized with vaccine against epidemic parotitis].

Autor: Goleva OV, Kharit SM, Cherniaeva TV, Aksenov OA, Davidkin I, Kolyshkin VM
Jazyk: ruština
Zdroj: Voprosy virusologii [Vopr Virusol] 2004 Sep-Oct; Vol. 49 (5), pp. 28-32.
Abstrakt: The morbidity structure was analyzed in children vaccinated against epidemic parotitis in 1993-2002. Eight children (4 with serous meningitis and 4 with lesions of the salivary glands) underwent virologic and immunologic examinations. The molecular typing of the SH-gene fragment of the parotitis virus showed the process in 7 cases to be provoked by the vaccination strain. Presumedly, progressing vaccine-associated meningitis inhibits antibody formation. The total incidence of vaccine-associated meningitis was shown, according to Saint Petersburg data, to be not high, which testifies to a low reactogenicity of the Russian vaccine strain.
Databáze: MEDLINE