Primary cardiac angiosarcoma with systemic metastases; a case report and review of the literature.

Autor: Larbcharoensub N; Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Thailand., Singhsnaeh A, Leelachaikul P
Jazyk: angličtina
Zdroj: Journal of the Medical Association of Thailand = Chotmaihet thangphaet [J Med Assoc Thai] 2004 Sep; Vol. 87 (9), pp. 1116-22.
Abstrakt: Angiosarcoma is a relatively uncommon primary malignant tumor of the heart derived from the endothelial cells. The authors report a case of primary cardiac angiosarcoma of the right atrium with pulmonary, hepatic, cerebellar and bony metastases in a 46-year-old man who clinically presented as pulmonary hemorrhage. The patient's occupational history had occasional exposure to polyvinyl chloride. The autopsy examination of the cardiac angiosarcoma characterized macroscopically by a right atrial tumor and histologically by anastomosing vascular channels and minute atypical pleomorphic endothelial cells. Immunohistological stainings were positive CD31, CD34 and focal positive factor VII-related antigen. Clinical and pathologic features with briefly reviewed relevant literatures are discussed This is the first reported description in the literature of a primary cardiac angiosarcoma with systemic metastases to multiple organs in Thailand.
Databáze: MEDLINE