[Bilateral acute retinal necrosis syndrome associated with meningoencephalitis caused by herpes simplex virus 2. A case report].
| Autor: | Cardine S; Service d'Ophtalmologie, Centre hospitalier Robert Ballanger, Aulnay sous Bois., Chaze PA, Bourcier F, Amara N, Prevost G, Ruhomauly H, Garandeau C, Maisonneuve L, Benzacken L |
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| Jazyk: | francouzština |
| Zdroj: | Journal francais d'ophtalmologie [J Fr Ophtalmol] 2004 Sep; Vol. 27 (7), pp. 795-800. |
| DOI: | 10.1016/s0181-5512(04)96216-x |
| Abstrakt: | Introduction: Acute retinal necrosis syndrome (ARN syndrome) is a rare viral disease with a poor prognosis in most cases. It is characterized by substantial ocular inflammation with progressive retinal necrosis, occlusive vasculitis and sometimes extraocular features. Case Report: We report the case of a 62-year-old woman who was referred for a suspicion of a stroke. Ophthalmological examination revealed a profound bilateral visual loss due to extensive retinal necrosis. The patient was immediately treated with antiherpetic drugs. ARN syndrome with meningoencephalitis caused by herpes simplex virus type 2 was confirmed by PCR studies performed on aqueous humor and cerebrospinal fluid. Herpes simplex virus 2 (IgG+ , IgM-) was probably reactivated after intrathecal injection of steroids because of pain associated with narrowing of the lumbar vertebral canal. The patient was treated with intravenous Acyclovir for 3 weeks. After 4 months, both retinas were detached. Discussion and Conclusion: ARN syndrome caused by herpes simplex virus 2 most often occurs after reactivation of the latent virus in patients with a neurological medical history or congenital infection. Antiviral treatment must begin early to decrease risks of bilateralization and complications. |
| Databáze: | MEDLINE |
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