Pulmonary alveolar proteinosis associated with psoriasis and complicated by mycobacterial infection: successful treatment with granulocyte-macrophage colony stimulating factor after a partial response to whole lung lavage.

Autor: Abdul Rahman JA; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia. alamine@pd.jaring.my, Moodley YP, Phillips MJ
Jazyk: angličtina
Zdroj: Respirology (Carlton, Vic.) [Respirology] 2004 Aug; Vol. 9 (3), pp. 419-22.
DOI: 10.1111/j.1440-1843.2004.00594.x
Abstrakt: Pulmonary alveolar proteinosis (PAP) is a rare lung disease. Although whole lung lavage is considered the most effective treatment, not every patient shows a complete response. The case ofa young man with PAP in association with psoriasis who underwent frequent whole lung lavage but only achieved remission following treatment with granulocyte-macrophage colony stimulating factor (GM-CSF) is reported. His lung problem was complicated by atypical mycobacterial infection,which resolved with treatment. The role of GM-CSF is discussed.
Databáze: MEDLINE