Detrusor pressure rise in a normal bladder.
Autor: | Wahl EF; Clark-Morrison Children's Urological Center, UCLA School of Medicine, Los Angeles, CA, USA. edwahl@alum.mit.edu, Churchill BM |
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Jazyk: | angličtina |
Zdroj: | BJU international [BJU Int] 2004 Oct; Vol. 94 (6), pp. 901-2. |
DOI: | 10.1111/j.1464-410X.2004.05056.x |
Abstrakt: | Objective: To determine the detrusor pressure rise of a normal bladder (P(cap,NL)) when filled to capacity. Patients and Methods: Twenty-four patients with an apparently normal bladder, i.e. with symptoms but whose cystometrogram (CMG) showed no pathology of any kind and a near-normal pressure vs volume plot, were selected from 218 clinical CMGs. A straight line was fitted to the PV plot of these CMGs and then the P(cap,NL) calculated, e.g. by a straight line extending to the point of the normal expected cystometric bladder capacity (V(cap.NL)). Published data relative to P(cap,NL) were evaluated and compared with the values obtained. Results: The mean (range) P(cap,NL) was 6 (4.5-7) cmH2O for patients with apparently normal bladders infused at the maximum physiological diuresis (MPD). This value was substantiated by three other studies of published values. The P(cap,NL) was 6 cmH2O at infusion rates of 10% of glomerular filtration rate (GFR), 10 cmH2O at 20% of GFR and 7-15 cmH2O for 3-10 times the infusion rate of 10% of GFR. Conclusion: P(cap,NL) is independent of age, size and sex and, at constant infusion rates of approximately MPD, will be 6. For infusion rates up to 35 mL/min, it is in the range of 6-15 cmH2O. |
Databáze: | MEDLINE |
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