[Results of the first Chilean registry of unstable angina. Clinical features, risk profile and treatment].
| Autor: | Corbalán R; Hospital Clínico de la Universidad Católica de Chile, Marcoleta 367, Piso 6. corbalan@med.puc.cl, Nazzal C, Eggers G, Bartolucci J, Prieto JC, Alcaíno M, Stockins B, Campos P, Dapelo A |
|---|---|
| Jazyk: | Spanish; Castilian |
| Zdroj: | Revista medica de Chile [Rev Med Chil] 2004 Feb; Vol. 132 (2), pp. 135-43. |
| DOI: | 10.4067/s0034-98872004000200001 |
| Abstrakt: | Background: From January 2000 to June 2002, the first Chilean registry of unstable angina was carried out, with the participation of 15 hospitals. Aim: To report the clinical and demographic features of 600 patients with unstable angina, their risk profile and prognosis. Material and Methods: The inclusion criteria for this prospective registry were a history of recent onset of chest pain (<48 hours) or a change in the character of previous angina, associated to ischemic electrocardiographic changes and/or positive markers of myocardial damage. Results: Mean age of the patients was 65 years and 37% were women. Among coronary risk factors, 63% had hypertension, 27% had diabetes, 52% had dyslipidemia, 31% smoked and 21% had a family history of atherosclerosis. On admission 94% of patients had chest pain, associated to ST segment depression in 44%, negative T waves in 28% and positive markers of myocardial damage in 30%. Fifty seven percent received intravenous nitroglycerin, 47% received oral nitrates, 69% beta blockers and 15%, calcium antagonists. Antithrombotic therapy included aspirin in 96%, heparin in 74%, ticlodipine or clopidogrel in 19% and IIb/IIIa inhibitors in 12%. A coronary angiogram was performed in 52%, angioplasty in 25% and coronary bypass surgery in 13%. Hospital mortality was 2.6%. The incidence of new ischemic events was: myocardial infarction in 2.8% recurrent ischemia in 9.5% and refractory ischemia in 2%. The incidence of adverse events increased according to a higher risk profile. Conclusions: The demographic and clinical features, treatment and mortality of these patients are similar to those reported in international registries, with a low mortality rate. |
| Databáze: | MEDLINE |
| Externí odkaz: |
|