| Autor: |
de Wolff JF; Department of Internal Medicine, Diaconessenhuis, Leiden, The Netherlands. jfdwolff@doctors.org.uk, Planken EV, den Ottolander GJ |
| Jazyk: |
angličtina |
| Zdroj: |
The Netherlands journal of medicine [Neth J Med] 2004 May; Vol. 62 (5), pp. 164-7. |
| Abstrakt: |
A 63-year-old woman presented to the internist with fatigue, cough, low-grade fever, splenomegaly and leucocytosis up to 130 x 10(9)/l. Although a diagnosis of chronic myelogenous leukaemia was initially entertained, she turned out to have a metastasised melanoma. The differential diagnosis and workup is discussed, as well as potential mechanisms by which the tumour could have induced the leucocytosis, such as the production of G-CSF or similar mediators, and the prognostic significance of this phenomenon. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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