Frequency of Helicobacter pylori antibodies in porto-systemic encephalopathy.
| Autor: | Sethar GH; Department of Medicine, Civil Hospital, Karachi., Ahmed R, Zuberi BF, Afsar S |
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| Jazyk: | angličtina |
| Zdroj: | Journal of the College of Physicians and Surgeons--Pakistan : JCPSP [J Coll Physicians Surg Pak] 2004 Sep; Vol. 14 (9), pp. 530-3. |
| DOI: | 09.2004/JCPSP.530533 |
| Abstrakt: | Objective: To study the frequency of Helicobacter pylori antibodies in patients presenting with porto-systemic encephalopathy due to liver disease. Study Design: An observational, cross-sectional study. Place and Duration of Study: Different medical units at Civil Hospital, Karachi between May 2001 and April 2002. Patients and Methods: During the study period, seventy-six patients of porto-systemic encephalopathy due to liver diseases were selected. These subjects were evaluated for hepatic encephalopathy grade, modified Child-Pugh classification and were managed according to the standard practices. These patients were evaluated for Helicobacter (H. pylori ) antibody status by ELISA(Abbott Laboratories) method. Results: Out of 76 patients studied and tested for H. pylori antibodies, 48(63.2%) were males and 28(36.8%) were females with age ranging between 17 and 85 years. Out of 76 patients who presented with porto-systemic encephalopathy, 59(77.6%) had a positive H. pylori antibody test. Thirty five of these were males and 24 were females. A significant number of patients who presented with higher grade of encephalopathy were H. pylori antibody positive (p < 0.001). Conclusion: In this study, frequency of H. pylori antibodies was significantly high in patients of porto-systemic encephalopathy. |
| Databáze: | MEDLINE |
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