| Autor: |
Silva FB; Center of Biological Sciences and Professions of Health, University of Sacred Heart, Bauru., Almeida JM, Sousa SM |
| Jazyk: |
angličtina |
| Zdroj: |
Brazilian oral research [Braz Oral Res] 2004 Apr-Jun; Vol. 18 (2), pp. 174-9. Date of Electronic Publication: 2004 Aug 05. |
| DOI: |
10.1590/s1806-83242004000200015 |
| Abstrakt: |
The objective of this study was to evaluate the irritant potential of propolis, Casearia sylvestris, Otosporin and saline solution (control). Twenty-eight male Wistar rats were selected, anesthetized and four experimental sites were designed on their backs. Injections of 2% Evans blue were intravenously administered in the lateral caudal vein and 0.1 ml of the tested solutions was injected intradermally into the experimental sites. The animals were killed 1/2, 1, 3 and 6 hours after the injection of the solutions. Each piece of skin containing the lesion was immersed in formamide and incubated at 45 masculine C for 72 h. After filtration, optical density was measured in a spectrophotometer. Data were statistically analyzed by a 2-way non-parametric test. The highest values of extracted dye were observed at 3 hours characterizing a peak in the inflammatory process. Propolis was the least irritant solution. The natural medicaments tested in this study may be a valuable alternative for endodontic treatment. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
