| Autor: |
Hsu FY; Yuanpei University of Science and Technology, 306 Yuanpei Street, Hsinchu 300, Taiwan. fyhsu@mail.yust.edu.tw, Tung CJ, Chen JC, Wang YL, Huang HC, Zamenhof RG |
| Jazyk: |
angličtina |
| Zdroj: |
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine [Appl Radiat Isot] 2004 Nov; Vol. 61 (5), pp. 881-5. |
| DOI: |
10.1016/j.apradiso.2004.05.048 |
| Abstrakt: |
In 1998, an epithermal neutron test beam was designed and constructed at the Tsing Hua Open-Pool Reactor (THOR) for the purpose of preliminary dosimetric experiments in boron neutron capture therapy (BNCT). A new epithermal neutron beam was designed at this facility, and is currently under construction, with clinical trials targeted in late 2004. Depth dose-rate distributions for the THOR BNCT test beam have been measured by means of activation foil and dual ion chamber techniques. Neutron and structure-induced gamma spectra measured at the test beam exit were configured into a source function for the Monte Carlo-based treatment planning code NCTPlan. Dose-rate scaling factors (DRSFs) were determined to normalize computationally derived dose-rate distributions with experimental measurements in corresponding mathematical and physical phantoms, and to thus enable accurate treatment planning using the NCTPlan code. A similar approach will be implemented in characterizing the new THOR epithermal beam in preparation for clinical studies. This paper reports the in-phantom calculated and experimental dosimetry comparisons and derived DRSFs obtained with the THOR test beam. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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