Novel N-aryl and N-heteroaryl sulfamide synthesis via palladium cross coupling.
| Autor: | Alcaraz L; Department of Medicinal Chemistry, AstraZeneca R&D Charnwood, Bakewell Road, Loughborough, Leics, LE11 5RH, United Kingdom. lilian.alcaraz@astrazeneca.com, Bennion C, Morris J, Meghani P, Thom SM |
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| Jazyk: | angličtina |
| Zdroj: | Organic letters [Org Lett] 2004 Aug 05; Vol. 6 (16), pp. 2705-8. |
| DOI: | 10.1021/ol049091l |
| Abstrakt: | A novel and efficient synthesis of N-aryl and N-heteroaryl sulfamides via an intermolecular palladium-catalyzed coupling process has been developed. The reactions proceeded with good to excellent yields and were tolerant of a wide range of functional groups. [reaction: see text] |
| Databáze: | MEDLINE |
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