| Autor: |
Plourde PJ; Department of Medical Microbiology, University of Nairobi, Kenya., Tyndall M, Agoki E, Ombette J, Slaney LA, D'Costa LJ, Ndinya-Achola JO, Plummer FA |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of infectious diseases [J Infect Dis] 1992 Oct; Vol. 166 (4), pp. 919-22. |
| DOI: |
10.1093/infdis/166.4.919 |
| Abstrakt: |
Sexually transmitted diseases (STDs) have a significant adverse effect on reproductive and child health worldwide. The control of STDs such as gonorrhea is therefore an absolute priority. Cefixime, an oral third-generation cephalosporin with in vitro activity similar to that of ceftriaxone, may be an effective candidate for the treatment of gonorrhea. The efficacy of a single oral 400-mg dose of cefixime was compared with that of a single intramuscular 250-mg dose of ceftriaxone for the treatment of Neisseria gonorrhoeae urethritis in 190 men and cervicitis in 46 women in Nairobi, Kenya. A bacteriologic cure was recorded in 100% of 63 evaluatable patients treated with ceftriaxone and 118 (98%) of 121 evaluatable patients treated with cefixime. Cefixime, as a single oral dose, is an effective alternative for the treatment of uncomplicated gonococcal urethritis in men and cervicitis in women. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
