| Autor: |
Jiang W; Department of Infectious Diseases, Fudan University Huashan Hospital, Shanghai, China., Kang L, Lu HZ, Pan X, Lin Q, Pan Q, Xue Y, Weng X, Tang YW |
| Jazyk: |
angličtina |
| Zdroj: |
Clinical and diagnostic laboratory immunology [Clin Diagn Lab Immunol] 2004 Jul; Vol. 11 (4), pp. 811-3. |
| DOI: |
10.1128/CDLI.11.4.811-813.2004 |
| Abstrakt: |
The aim of this study was to establish reference ranges for lymphocyte subsets in Chinese adults. Venous blood specimens were obtained from 614 healthy, human immunodeficiency virus (HIV)-seronegative adults in Shanghai. Flow cytometry was used to determine percentages and absolute numbers of CD4 and CD8 T lymphocytes. Mean values for CD4 and CD8 lymphocytes were 727 and 540 cells/microl, respectively, yielding a CD4/CD8 ratio of 1.49. While CD8 lymphocyte values varied with age and gender, no significant differences in CD4 lymphocyte values were observed. Shanghai adults had approximately 100 fewer CD4 lymphocytes/microl on average than Caucasians, suggesting that lower CD4 lymphocyte cutoffs for classifying and monitoring HIV infection may be needed in China. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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