| Autor: |
Ricci Lucas SR; Faculdade de Medicina, Veterinária e Zootecnia, Universidade de São Paulo, Brazil., Pereira Coelho BM, Marquezi ML, Franchini ML, Miyashiro SI, De Benedetto Pozzi DH |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of the American Animal Hospital Association [J Am Anim Hosp Assoc] 2004 Jul-Aug; Vol. 40 (4), pp. 292-9. |
| DOI: |
10.5326/0400292 |
| Abstrakt: |
A chemotherapeutic protocol using carmustine in combination with vincristine and prednisone was tested in dogs with multicentric malignant lymphosarcoma. Of seven dogs treated, six (85.7%) achieved complete remission. A partial response occurred in one dog. Median survival time was 224 days (mean 386 days), and median duration of remission was 183 days (mean 323 days). Marked neutropenia was observed following carmustine administration. There were no significant alterations in platelets and red blood cell counts during treatment, and no abnormalities attributable to the chemotherapy were found in serum biochemical profiles. Results of this study showed that carmustine is an effective alternative option in the treatment of canine lymphosarcoma. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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