Hypoglycemic activity of Withania coagulans Dunal in streptozotocin induced diabetic rats.

Autor: Hemalatha S; Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi, India. hemalatha111@rediffmail.com, Wahi AK, Singh PN, Chansouria JP
Jazyk: angličtina
Zdroj: Journal of ethnopharmacology [J Ethnopharmacol] 2004 Aug; Vol. 93 (2-3), pp. 261-4.
DOI: 10.1016/j.jep.2004.03.043
Abstrakt: Administration of aqueous extract of fruits of Withania coagulans Dunal significantly lowered the blood sugar, serum cholesterol, serum LPO, and hepatic LPO levels at the highest concentration of 1g/kg; p.o. in streptozotocin induced diabetic rats. In normal rats as well the blood sugar levels were significantly decreased following treatment with the above drug. Withania coagulans also exhibited free radical scavenging activity in an in vitro system using DPPH.
Databáze: MEDLINE