[Spontaneous and mitogen-induced production of proinflammatory cytokines (interleukin-1 and tumor necrosis factor-alpha) in patients with chronic chlamydia infection of urogenital system].

Autor: Driians'ka VIe, Drannik HM, Vashchenko SM, Fesenkova VI, Papakina VS
Jazyk: ukrajinština
Zdroj: Likars'ka sprava [Lik Sprava] 2004 Mar (2), pp. 35-9.
Abstrakt: The article contributes to studying functional activity of mononuclear and macrophage immune cells by spontaneous and induced production of IL-1 and TNF-alpha cytokines in patients with chronic urogenital clamidiosis. The patients with monoinfection were shown to have high level of IL-1 and low level of TNF-alpha, while the patients with mixed infection of urogenital tract presented with the high production of TNF-alpha. The cells activation raise cytokines production not to the level observed among healthy persons. It suggests decreasing compensatory regulation in yet higher activated cells.
Databáze: MEDLINE