In vivo protein markers of human peritoneal mesothelial cells: do they differ according to their anatomical sites?
| Autor: | Serre V; Laboratoire Cytosquelette et Développement, CNRS UMR 7000, Faculté de Médecine Pitié-Salpêtrière, Paris, France., Tézenas du Montcel S, Kontula L, Simon M, Perret E, Nédellec P, Vicart P, Duron JJ |
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| Jazyk: | angličtina |
| Zdroj: | The European journal of surgery. Supplement. : = Acta chirurgica. Supplement [Eur J Surg Suppl] 2003 Jul (588), pp. 40-5. |
| Abstrakt: | Objective: To highlight the in vivo protein markers in human peritoneal mesothelial cells according to their anatomical distribution and their interest in theories of peritoneal repair. Design: Clinical laboratory study. Setting: University Hospital, France. Patients: Sampling of mesothelial cells during 8 laparotomies by impression smears. Main Outcome Measures: Immunochemical semiquantitative measures of proteins. Results: There were uniform ratios of protein markers among the whole peritoneal mesothelial cell population, whatever their anatomical origin (liver, stomach, omentum, small bowel, and abdominal wall). Conclusion: This is consistent with the surrounding uninjured mesothelial cells or the exfoliated mesothelial cells, or both, having a role in postoperative peritoneal mesothelial repair. |
| Databáze: | MEDLINE |
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