| Autor: |
Arink AM; Debye Institute, Department of Metal-Mediated Synthesis, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands., Braam TW, Keeris R, Jastrzebski JT, Benhaim C, Rosset S, Alexakis A, van Koten G |
| Jazyk: |
angličtina |
| Zdroj: |
Organic letters [Org Lett] 2004 Jun 10; Vol. 6 (12), pp. 1959-62. |
| DOI: |
10.1021/ol049457u |
| Abstrakt: |
[structure: see text] Full conversion and enantioselectivities up to 83% have been obtained in the conjugate addition reactions of diethyl zinc to Michael acceptors catalyzed by well-defined (chiral) copper(I) aminoarenethiolates. Interesting differences between organozinc or Grignard reagents have been found: for cyclic enones R(2)Zn reagents afford better results, whereas earlier work showed that RMgX reagents react more selectively with acyclic enones. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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