[Primary testicular lymphomas. Clinicopathologic analysis of 10 cases. Experience at the National Institute of Cancerology in Mexico City].

Autor:	Avilés-Salas A; Departamento de Patología del Instituto Nacional de Cancerología, México, DF. alejandroaviles2001@yahoo.com, Turbiner-Miasnikova J, Labardini-Méndez JR, Sobrevilla-Calvo Pde J
Jazyk:	Spanish; Castilian
Zdroj:	Gaceta medica de Mexico [Gac Med Mex] 2004 Mar-Apr; Vol. 140 (2), pp. 123-8.
Abstrakt:	Unlabelled: Non-Hodgkin lymphoma is the most common primary testicular neoplasm of older men but is rare in young men. The vast majority of primary testicular lymphomas (PTL) are intermediate- to high-grade lymphomas. Objective: To describe the clinical, morphologic, and immunophenolypic characteristics of PTL seen in a referral center. Material and Methods: We reviewed the cases of PTL seen from 1986 to 1999. We obtained data of laboratory, tests, clinical course, treatment, and immunohistochemical studies. Results: 10 patients with diagnosis of PTL were identified. Median age was 62.3 years (range 42-81 years), and nine patients underwent orchiectomy as initial therapeutic procedure. Other treatment modalities after diagnosis included combination chemotherapy (60%) and combination radiotherapy (20%). Histologically, testes showed diffuse dense infiltration of large lymphoma cells. All cases were classified as diffuse large cell lymphoma according to REAL classification. Eight cases were studied with use of paraffin-section immunoperoxidase, 7/8 tumors were B-lineage lymphomas, and one was a T-lineage lymphoma.
Databáze:	MEDLINE
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