| Autor: |
Rayner CF; Department of Chest Medicine, St George's NHS Trust, Blackshaw Road, London SW17 0QT, UK., Grubnic S |
| Jazyk: |
angličtina |
| Zdroj: |
Best practice & research. Clinical rheumatology [Best Pract Res Clin Rheumatol] 2004 Jun; Vol. 18 (3), pp. 381-410. |
| DOI: |
10.1016/j.berh.2004.03.004 |
| Abstrakt: |
Patients with systemic autoimmune disease may present with a number of different pulmonary manifestations. In order to recognise, diagnose and manage these manifestations, it is necessary to have a working knowledge of the anatomy and physiology of the thorax. This chapter will describe the clinical symptoms and clinical examination findings in patients who may have underlying pulmonary disease. It will describe the investigations that can be used to confirm or refute a possible diagnosis and describe approaches to managing these complex clinical cases. The importance of multidisciplinary team working using the skills of clinicians, radiologists and pathologists will be highlighted. The use of high-resolution computed tomography scanning of the thorax to help to delineate the type of interstitial lung disease will be described and some of the newer modalities available for the treatment of pulmonary hypertension introduced. By the end of the chapter, the reader should understand that patients with a single underlying autoimmune disease may present with one or more pulmonary manifestations and that different autoimmune diseases may present with similar pulmonary manifestations. This heterogeneity poses both diagnostic and treatment challenges, and many questions still remain regarding optimal treatment. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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