| Autor: |
Bastos KR; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, Sao Paulo, Brazil. krbastos@usp.br, Marinho CR, Barboza R, Russo M, Alvarez JM, D'Império Lima MR |
| Jazyk: |
angličtina |
| Zdroj: |
Microbes and infection [Microbes Infect] 2004 May; Vol. 6 (6), pp. 630-6. |
| DOI: |
10.1016/j.micinf.2004.02.012 |
| Abstrakt: |
The present review illustrates the current knowledge on the autocrine effect of IL-12, and the putative contribution of IL-23, on macrophages and dendritic cells, focusing on cell activation and microbicidal activity. Here, we present convincing evidence that IL-12 is not only a connective element between accessory cells and lymphocytes, but it is also a key molecule for programming the macrophage and dendritic cell functions. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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