| Autor: |
Amin M; CHIR Group in Matrix Dynamics and Dental Research Institute, University of Toronto, Toronto, Ontario, Canada M5G 1G6., Ho AC, Lin JY, Batista da Silva AP, Glogauer M, Ellen RP |
| Jazyk: |
angličtina |
| Zdroj: |
Infection and immunity [Infect Immun] 2004 Jun; Vol. 72 (6), pp. 3650-4. |
| DOI: |
10.1128/IAI.72.6.3650-3654.2004 |
| Abstrakt: |
Treponema denticola and its major outer sheath protein (Msp) induce actin reorganization in fibroblasts. We adapted a barbed-end labeling/imaging assay to monitor Msp-induced subcortical actin filament assembly in neutrophils and fibroblasts. Msp, at an actin-reorganizing concentration, inhibited migration of these dissimilar cell types, whose cytoskeletal functions in locomotion and phagocytosis are crucial for immunity and healing of peripheral infections. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
