| Autor: |
Motameni AR; Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, USA., Juncadella IJ, Ananthanarayanan SK, Hedrick MN, Huet-Hudson Y, Anguita J |
| Jazyk: |
angličtina |
| Zdroj: |
Infection and immunity [Infect Immun] 2004 Jun; Vol. 72 (6), pp. 3638-42. |
| DOI: |
10.1128/IAI.72.6.3638-3642.2004 |
| Abstrakt: |
A Salmonella enterica serovar Typhimurium aroA-deficient delivery system was used to target the immunosuppressive protein Salp15 to antigen-presenting cells. In vitro and in vivo infections with Salp15-containing Salmonella resulted in an impaired CD4(+)-T-cell activation, suggesting that the protein was produced by antigen-presenting cells in a physiologically active form. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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