| Autor: |
Diessler ME; Institute of Pathology, Faculty of Veterinary Sciences, National University of La Plata, La Plata, Argentina. diessler@fcv.unlp.edu.ar, Castellano MC, Massone AR, Portiansky EL, Allende MG, Idiart JR, Gimeno EJ |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine [J Vet Med A Physiol Pathol Clin Med] 2003 Nov; Vol. 50 (9), pp. 452-6. |
| DOI: |
10.1046/j.1439-0442.2003.00573.x |
| Abstrakt: |
Lymphangiosarcoma is a rare tumour in domestic animals arising from lymphatic endothelial cells. Occasionally, microscopic differentiation with haemangiosarcoma may be difficult. The aim of the present study was to describe a lymphangiosarcoma in a 1-year-old female Doberman Pinscher dog and to characterize its lectinhistochemical binding pattern as compared with that of haemangiosarcoma. The dog was presented because of a cutaneous painful swelling located in the left axilla. Histological diagnosis confirmed lymphangiosarcoma. The dog was killed. Necropsy revealed mediastinal lymph nodes' involvement. Twenty lectins were tested in tissue sections of this case as well as in four haemangiosarcomas from other dogs. Staining intensity was issued upon optical density determinations. Percentage of lectinhistochemical staining area was also conducted. RCA-I showed the most intense and wide distributed labelling pattern for lymphangiosarcoma. PHA-E was the counterpart for haemangiosarcoma. Should similar results be obtained in further studies, such differences could aid in the differential diagnosis between lymphangiosarcoma and haemangiosarcoma when histological pictures were not conclusive. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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