Microlithiasis: an important cause of "idiopathic" acute pancreatitis?

Autor: Venneman NG; Gastrointestinal Research Unit, Depts. of Gastroenterology and Surgery, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands., van Brummelen SE, van Berge-Henegouwen GP, van Erpecum KJ
Jazyk: angličtina
Zdroj: Annals of hepatology [Ann Hepatol] 2003 Jan-Mar; Vol. 2 (1), pp. 30-5.
Abstrakt: Microlithiasis is the underlying cause in a significant proportion of patients with "idiopathic" acute pancreatitis. The mechanism appears to be a relative deficiency of phosphatidylcholine in bile, with fast and extensive cholesterol crystallization as a result. Diagnosis of microlithiasis by microscopic detection of cholesterol crystals in bile is important and should lead to appropriate therapy (cholecystectomy, endoscopic sphincterotomy or ursodeoxycholic acid maintenance therapy).
Databáze: MEDLINE