Experimental Mycoplasma hominis infection of the genital tract in BALB/c mice.

Autor: Shkarupeta MM; Institute of Physicochemical Medicine, Russian Ministry of Health, Moscow., Lazarev VN, Govorun VM
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2004 Jan; Vol. 137 (1), pp. 53-5.
DOI: 10.1023/b:bebm.0000024386.33789.0f
Abstrakt: We studied the ability of laboratory and clinical strains of Mycoplasma hominis to colonize the genital tract mucosa in BALB/c mice. Colonization with mycoplasma occurred only in mice receiving estrogen. Mycoplasma hominis strains obtained after 3-fold passage through the vaginal mucosa in mice and administered intravaginally in a dose of 0.5 x 10(8) CFU/ml caused infection in 100% animals. Inflammation in the lower genital tract was reduced by the 8th week after infection.
Databáze: MEDLINE