Postpartum amenorrhoea-galactorrhoea associated with hyperprolactinaemia and pituitary enlargement in primary hypothyroidism.

Autor: Kroese JM; Department of Internal Medicine, MCRZ-Clara Hospital, Rotterdam, The Netherlands. jmkroese@noknok.nl, Grootendorst AF, Schelfhout LJ
Jazyk: angličtina
Zdroj: The Netherlands journal of medicine [Neth J Med] 2004 Jan; Vol. 62 (1), pp. 28-30.
Abstrakt: We report a 36-year-old woman with primary hypothyroidism revealed by postpartum amenorrhoea-galactorrhoea associated with hyperprolactinaemia and suprasellar pituitary enlargement on magnetic resonance imaging (MRI). On thyroid hormone replacement therapy all clinical, biochemical, radiological and endocrine abnormalities disappeared. Hyperplasia of pituitary thyrotrophs and/or lactotrophs seems to be responsible for the pituitary enlargement seen on MRI.
Databáze: MEDLINE