| Autor: |
Tavechio AT; Seção de Bacteriologia, Instituto Adolfo Lutz, São Paulo, SP, 01246-902, Brasil., Marques LR, Abe CM, Gomes TA |
| Jazyk: |
angličtina |
| Zdroj: |
Memorias do Instituto Oswaldo Cruz [Mem Inst Oswaldo Cruz] 2004 Feb; Vol. 99 (1), pp. 81-3. Date of Electronic Publication: 2004 Mar 31. |
| DOI: |
10.1590/s0074-02762004000100014 |
| Abstrakt: |
The enteropathogenic role of cytotoxic necrotizing factor (CNF)-producing Escherichia coli was investigated by searching cnf genes among 2074 isolates from 200 children with and 200 without acute diarrhea in Brazil. Fourteen (7%) cases versus 10 (5%) control children carried at least one cnf positive isolate (P = 0.50) and most isolates expressed CNF type 1. DNA sequences of virulence factors of extraintestinal pathogenic E. coli (ExPEC) were detected in 78.6% of CNF1-producing isolates. Besides not being associated with human acute diarrhea, the CNF1-producing isolates here identified may represent potential ExPEC transitorily composing the normal intestinal flora. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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