| Autor: |
Arrington MP; UCB Research, Inc, 840Memorial Drive, Cambridge, MA 02139, USA., Brown C, Schwartz CE |
| Jazyk: |
angličtina |
| Zdroj: |
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2004 Apr 05; Vol. 14 (7), pp. 1807-9. |
| DOI: |
10.1016/j.bmcl.2003.12.105 |
| Abstrakt: |
Treatment of dextromethorphan 1 with various alkylating agents followed by base treatment led to Hoffman-type elimination reactions to produce a series of tricyclic derivatives, 6. These derivatives were characterized in vitro as sigma-1 receptor ligands. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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