| Autor: |
Handa BK; Department of Physical Chemistry, Roche Products Limited, Welwyn Garden City, Hertfordshire, England., Kay C |
| Jazyk: |
angličtina |
| Zdroj: |
International journal of peptide and protein research [Int J Pept Protein Res] 1992 Nov; Vol. 40 (5), pp. 363-9. |
| DOI: |
10.1111/j.1399-3011.1992.tb00312.x |
| Abstrakt: |
Two small peptide substrates for HIV-1 proteinase were synthesised. The sequences chosen were basically from that of the gag-pol protein, which is the natural substrate for the proteinase. To protect these peptides from the attack of exopeptidases, the N- and C-termini were suitably protected, which also makes these substrates specific to HIV-proteinase and eliminates the requirement for highly purified enzyme. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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