[The preventive activity of monoclonal antibodies specific to the lipopolysaccharide of Francisella tularensis].

Autor: Khlebnikov VS, Vetchinin SS, Grechko GK, Averina AA, Golovlev IR, Averin SF, Zhemchugov VE, Konovalov SI, Anisimov GA, Afanas'ev SS
Jazyk: ruština
Zdroj: Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 1992 (9-10), pp. 67-70.
Abstrakt: The preventive activity of five monoclonal antibodies (McAb) in experimental tularemia was evaluated. McAb produced by hybridoma FB11-k (IgG2a), specific to F. tularensis lipopolysaccharide, prevented the death of mice and guinea pigs infected with F. tularensis virulent strain 503 of the holarctic subspecies.
Databáze: MEDLINE