| Autor: |
Gruzina VD; Gauze Institute of New Antibiotics, Russian Academy of Medical Sciences, ul. Bol'shaya Pirogovskaya 11, Moscow, Russia., Gorbatiuk EV, Efremenkova OV, Filippova SN, El'-Registan GI, Dudnik IuV |
| Jazyk: |
ruština |
| Zdroj: |
Mikrobiologiia [Mikrobiologiia] 2003 Nov-Dec; Vol. 72 (6), pp. 770-4. |
| Abstrakt: |
Spore germination in streptomycetes was shown to be stimulated by exogenously added A-factor. Agar medium either containing or not containing A-factor was inoculated with spore suspensions of three strains differing in their ability to produce regulators of the A-factor group: Streptomyces griseus 773, which produces A-factor and two its lower homologs, S. coelicolor A3(2), which forms six AcL-factors (A-factor analogues), and S. avermitilis JCM5070, which fails to form regulators of this group. The count of the grown colonies showed that exogenous A-factor stimulated spore germination in strains that were themselves able to synthesize regulators of the A-factor group. In S. griseus 773, the number of germinated spores increased by 67% on average after the addition A-factor to the medium in an amount 10 micrograms/ml. In strain S. coelicolor A3 (2), the number of germinated spores increased by 75% after the addition of 1 microgram/ml of A-factor. During germination of the S. avermitilis JCM5070 spores, no changes in the CFU number was observed after the addition of A-factor. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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