[Primary urothelial carcinoma of the bulbomembranous urethra. Histologic and immunohistochemical study of a case].

Autor:	Parada D; Servicio de Anatomía Patológica, Hospital Vargas de Caracas, Caracas, Venezuela. parada@cantv.net, Páez A, Acosta M, Caricote L, Trujillo E, Luigi JC, Farías RM
Jazyk:	Spanish; Castilian
Zdroj:	Archivos espanoles de urologia [Arch Esp Urol] 2003 Dec; Vol. 56 (10), pp. 1144-7.
Abstrakt:	Objective: We report a case of a primary urothelial carcinoma of the bulbomembranous urethra, with special emphasis on histopathological and immunohistochemical findings. Methods/results: A 63-year-old man presented urethral obstruction symptoms. A radical phalectomy was performed and a 4.5 x 4 cm bulbomembranous urethral tumor was observed. Histopathological analysis disclosed an urothelial carcinoma, that showed positive immunostaining for cytokeratin AE1/AE3, cytokeratin 7, carcinoembrionic antigen and epithelial membrane antigen. The patient received radiotherapy and adjuvant chemotherapy and is currently free of disease. Conclusion: Posterior male urothelial carcinoma of the urethra is a rare neoplasm that usually is mistaken clinically for a benign lesion. The diagnostic is generally made in advanced stages with a poor therapeutical response.
Databáze:	MEDLINE
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